Publications

List of Publications

32.  Soubhye, J., Chikh Alard, I., Aldib, I., Prévost, M., Gelbcke, M., De Carvalho, A., Furtmüller, P.G., Obinger, C., Flemmig, J., Tadrent, S., Meyer, F., Rousseau, A., Neve, J., Mathieu, V., Zouaoui Boudjeltia K., Dufrasne F.M.U., Van Antwerpen, P.G. Discovery of novel potent reversible and irreversible myeloperoxidase inhibitors using virtual screening procedure. J. Med. Chem. (2017), in press. [DOI]

31.  Gau, J., Prévost, M., Van Antwerpen, P., Sarosi, M.B., Rodewald, S., Arnhold, J., Flemmig, J. Tannins and tannin-related derivatives enhance the (pseudo-)halogenating activity of lactoperoxidase. J. Nat. Prod. 80 (2017) 1328-1338. [DOI; PubMed]

30. Flemmig, J., Schlorke, D., Kuehne, F.-W., Arnhold, J. Inhibition of the heme-induced hemolysis of red blood cells by the chlorite-based drug WF10. Free Rad. Res. 50 (2016) 1396-1407.

29. Schlorke, D., Atosuo J., Flemmig, J., Lilius, E.-M., Arnhold, J. Impact of cyanogen iodide in killing of Escherichia coli by the lactoperoxidase-hydrogen peroxide-(pseudo)halide system. Free Radic. Res. 50 (2016) 1287-1295.

28. Schlorke, D., Flemmig, J., Gau, J., Furtmüller, P.G., Obinger, C., Arnhold, J. New insights into thiocyanate oxidation by human myeloperoxidase. J. Inorg Biochem 162 (2016) 117-126. 

27. Gau, J., Furtmüller, P.G., Obinger, C., Prévost, M., van Antwerpen, P., Arnhold, J., Flemmig, J. Flavonoids as promoters of the (pseudo-)halogenating activity of lactoperoxidase and myeloperoxidase. Free Radic. Biol. Med. 97 (2016) 307-319.

26. Schlorke, D., Flemmig, J., Birkemeyer, C., Arnhold, J. headspace-GC-MS bestätigt: ICN wird durch Lactoperoxidase gebildet. Shimadzu Newsletter 1 (2016)6-7.

25. Flemmig, J., Schwarz, P., Bäcker, I., Leichsenring, A., Lange, F., Arnhold, J. Fast and specific assessment of the halogenating peroxidase activity in leukocyte-enrichted blood samples. J. Vis. Exp. 113 (2016) e54484.

24. Leichsenring, A., Bäcker, I., Furtmüller, P.G., Obinger, C., Lange, F., Flemmig, J. Long-term effects of (-)epigallocatechin gallate (EGCG) on pristane-induces arthritis (PIA) in female Dark Agouti rats. PLoS One 11 (2016) e0152518.

23. Flemmig, J., Gau, J., Schlorke, D., Arnhold, J. Lactoperoxidase as a potential drug target. Expert Opin. Ther. Targets 20 (2016) 447-461.

22. Flemmig, J., Gau, J., Arnhold, J. Enzymassay zur Untersuchung des aktivitätssteigernden Effekts von Phytopharmaka auf die katalytische Aktivität der Laktoperoxidase. Z. Phytother. 36 (2015), Conference Paper.

21. Flemmig, J., Leichsenring, A., Lange, F. Myeloperoxidase - ein neuer Marker zur Erforschung von Entzündungen? Biospektrum 21 (2015) 725-727.

20. Flemmig, J., Gau, J., Schlorke, D., Arnhold, J. Lactoperoxidase as a potential drug target. Exp. Opinion Therap. Targets 11 (2015) 1-15.

19. Schlorke, D., Flemmig, J., Birkenmeyer, C., Arnhold, J. Formation of cyanogen iodide by lactoperoxidase. J. Inorg. Biochem. 154 (2016) 35-41.

18. Gau, J., Furtmüller, P.G., Obinger, C., Arnhold, J., Flemmig, J. Enhancing hypothiocyanite production by lactoperoxidase - mechanism and chemical properties of promoters. Biochem. Biophys. Rep. 4 (2015) 257-267.

17. Flemmig, J., Schwarz, P., Bäcker, I., Leichsenring, A., Lange, F., Arnhold, J. Rapid and reliable determination of the halogenating peroxidase activity in blood samples. J. Immunol. Meth. 415 (2015) 46-56.

16. Flemmig, J., Zschaler, I., Remmler, J., Arnhold, J. (2015). Detection of halogenating activity of haem peroxidases in leukocytes by aminophenyl fluorescin. Free Radic. Res. 49, pp. 768-776.

15. Flemmig, J., Noetzel, I., Arnhold, J., Rauwald, H.-W. (2015). Leonurus cardiaca L. herb estracts and their constitutents promote lactoperoxidase activity. J. Funct. Foods 17, pp.  328-339.

14. Jakopitsch, C., Pirker, K.F., Flemmig, J., Hofbauer, S., Schlorke, D., Furtmüller, P.G., Arnhold, J., Obinger, C. (2014). Mechanism of reaction of chlorite with mammalian heme peroxidases. J. Inorg. Biochem 135 , pp. 10-19.

13. Flemmig, J., Rusch, D., Czerwinska M.E., Rauwald, J.-W., Arnhold, J.  Components of a standardised olive leaf dry extract (Ph. Eur.) promote hypothiocyanite production by lactoperoxidase.Arch. Biochem. Biophys. 549, pp. 17-25.

12. Flemmig, J., Remmler, J., Röhring, F., Arnhold, J. (2014). (-)-Epicatechin regenerates the chlorinating activity of myeloperoxidase in vitro and in neutrophil granulocytes. J. Inorg. Biochem. 130, pp. 84-91.

11. Flemmig, J., Zschaler, J., Remmler, J., Arnhold, J. (2012). The fluorescein-derived dye aminophenyl-fluorescein (APF) is a suitable tool to detect HOBr producing activity in eosinophils. J. Biol. Chem. 287(33), pp. 27913-27923.

10. Pichert, A., Schlorke, D., Zschaler, J., Fleddermann, J., Schönberg, M., Flemmig, J., Arnhold, J. (2012). Early events in apoptosis induction in polymorphonuclear leukocytes. In: Aleksandar Laznica (Ed.). Floy Cytometry/Book 1, Vol. 1 (ISBN 980-953-0626-5). Rijeka, Croatia: Intech. pp. 357-372.

9.    Kamčeva, T., Flemmig, J., Demnjanović,  B., Arnhold, J., Mijatović, A., Petković, M.  (2011). Inhibitory effect of platinum and ruthenium bipyridyl complexes on porcine pancreatic phospholipase A2. Metallomics, 3(10), pp. 1056-2063.

8.    Flemmig, J., Kuchta, K., Arnhold, J., Rauwald, H.W. (2010). Olea europaea leaf (Ph. Eur.) extract as well as several of its isolated phenolics inhibit the gout-related enzyme xanthine oxidase. Phytomedicine, pp. 561-566.

7.    Prost, S., Knapp, M., Flemmig, J., Hufthammer, A.K., Kosintsev, P., Stiller, M., Hofreiter, M. (2010). A phantom extinction? New insights into extinction dynamics of the Don-hare Lepus tanaiticus. J. Evol. Biol., 23(9), pp. 2022-2029.

6.    Arnhold, J., Flemmig, J. (2010). Human myeloperoxidase in innate and acquired immunity. Arch. Biochem. Biophys., 500(1), pp. 92-106.

5.    Flemmig, J., Arnhold, J. (2010). Interaction of hypochlorous acid and myeloperoxidase with phosphatidylserine in the presence of ammonium ions. J. Inor. Biochem., 104(7), pp. 759-764.

4.    Kirchner, T., Flemmig, J., Furtmüller, P.G., Obinger, C., Arnhold, J. (2010). (-)-Epicatechin enhances the chlorinating activity of human myeloperoxidase. Arch. Biochem. Biophys., 495(1), pp. 21-27.

3.    Flemmig, J., Spalteholz, H., Schubert, K., Meyer, S., Arnhold, J. (2009). Modification of  phosphatidylserine by hypochlorous acid. Chem. Phys. Lipids, 161(1), pp. 44-50.

2.    Flemmig, J., Leßig, J., Reibetanz, U., Dautel, P., Arnhold, J. (2008). Non-vital polymorphonuclear leukocytes express myeloperoxidase on their surface. Cell Physiol. Biochem., 21(4), pp. 287-296.

1.    Flemmig, J., Arnhold, J. (2007). Ferrous ion-induced strand breaks in the DNA plasmid pBR322 are not mediated by hydrogen peroxide. Eur. Biophys. J., 36(4-5), pp. 377-384.     

 

 

letzte Änderung: 12.07.2017